Correlation of bacterial colonization status between mother and child: the Generation R Study

Ankie Lebon; Henriëtte A Moll; Mehri Tavakol; Willem J van Wamel; Vincent W V Jaddoe; Albert Hofman; Henri A Verbrugh; Alex van Belkum

doi:10.1128/JCM.01799-09

Correlation of bacterial colonization status between mother and child: the Generation R Study

J Clin Microbiol. 2010 Mar;48(3):960-2. doi: 10.1128/JCM.01799-09. Epub 2009 Nov 25.

Authors

Ankie Lebon¹, Henriëtte A Moll, Mehri Tavakol, Willem J van Wamel, Vincent W V Jaddoe, Albert Hofman, Henri A Verbrugh, Alex van Belkum

Affiliation

¹ Department of Paediatrics, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands.

Abstract

Determinants of bacterial colonization in children have been described. In the Generation R Study, a population-based cohort study, we determined whether the colonization statuses of mothers and children are correlated. Such a correlation was observed for Staphylococcus aureus and Haemophilus influenzae. Direct transmission, genetic susceptibility and/or unidentified environmental factors may play a role here.

MeSH terms

Adult
Bacterial Typing Techniques
Carrier State / microbiology*
Carrier State / transmission*
Child, Preschool
Cohort Studies
DNA Fingerprinting
Electrophoresis, Gel, Pulsed-Field
Female
Haemophilus Infections / microbiology*
Haemophilus Infections / transmission*
Humans
Infant
Infectious Disease Transmission, Vertical*
Male
Molecular Epidemiology
Mothers
Staphylococcal Infections / microbiology*
Staphylococcal Infections / transmission*