Estimating the neurocognitive effects of an early intervention program for children with prenatal alcohol exposure

Can J Clin Pharmacol. 2009 Fall;16(3):e453-9. Epub 2009 Nov 19.

Abstract

Background: Animal studies suggest that early intervention in pups exposed heavily to ethanol in utero can mitigate their neurocognitive damage. No human studies on this promising mechanism exists.

Methods: Breaking the Cycle is an early intervention program for drug-and alcohol addicted mothers and their young children. We compared BSID-III scores between infants heavily exposed to ethanol and a group exposed only to drugs of abuse, mainly cocaine. Both groups benefited from all aspects of our early intervention program.

Results: The two groups did not differ in any aspect of the BSID-III. These data are in contradistinction to the damage seen in heavily ethanol- exposed infants not benefiting from early intervention.

Conclusions: This pilot suggests that early intervention may mitigate some of the well described damages caused by heavy in utero alcohol exposure.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcoholism / complications*
  • Child
  • Child Development / drug effects
  • Cocaine-Related Disorders / complications
  • Cognition / drug effects
  • Developmental Disabilities / diagnosis*
  • Developmental Disabilities / etiology
  • Developmental Disabilities / psychology
  • Early Intervention, Educational*
  • Female
  • Fetal Alcohol Spectrum Disorders / diagnosis
  • Fetal Alcohol Spectrum Disorders / etiology
  • Fetal Alcohol Spectrum Disorders / psychology
  • Humans
  • Infant, Newborn
  • Language Development Disorders / chemically induced
  • Language Development Disorders / diagnosis
  • Language Development Disorders / psychology
  • Maternal-Fetal Exchange
  • Motor Activity / drug effects
  • Pilot Projects
  • Pregnancy
  • Pregnancy Complications*
  • Prenatal Exposure Delayed Effects / diagnosis*
  • Substance-Related Disorders / complications*