Rotavirus positive stool specimens collected from children less than 5-year-old admitted to Yangon Children's Hospital for diarrhoea were analysed for their G and P genotypes. In 2004, rotavirus was detected in 57% of 1004 samples tested with G3 and P[8] being the most common genotypes identified. Corresponding figures in 2005, were 55% of 1175 samples positive for rotavirus with G3 and P[4] genotypes being most common. The most common G and P combinations were G3P[8] and G1P[8], with some unusual combinations (G1P[4], G1P[6] and G3P[4]) also being identified. In Myanmar, ongoing rotavirus surveillance to understand the distribution of G and P genotypes will be important for monitoring the impact of rotavirus vaccines following their introduction into the infant immunization schedule.