Molecular epidemiology of G9 rotavirus strains in children with diarrhoea hospitalized in Mainland China from January 2006 to December 2007

Vaccine. 2009 Nov 20:27 Suppl 5:F40-5. doi: 10.1016/j.vaccine.2009.08.073.

Abstract

Rotavirus was detected in 52% of 2328 stool specimens collected from children with acute gastroenteritis admitted to three sentinel hospitals in Mainland China from January 2006 to December 2007. G3P[8] (42%) was the most common strain. Despite being common globally, only 18 (2%) G9-positive samples were identified. The VP7, VP4, VP6, and NSP4 genes were sequences for 13 of the G9 strains with G9P[8] being most common and showing the same origin as G9 strains reported in other countries. One G9P[6] strain was possibly derived by reassortment between earlier Chinese G9 strains and more recent local P[6] strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • China / epidemiology
  • Diarrhea / epidemiology*
  • Diarrhea / virology
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Genes, Viral
  • Genotype
  • Humans
  • Infant
  • Molecular Epidemiology
  • Prevalence
  • RNA, Viral / genetics
  • Rotavirus / genetics*
  • Rotavirus Infections / epidemiology*
  • Sentinel Surveillance
  • Sequence Analysis, RNA

Substances

  • RNA, Viral