Asian perspectives in the management of inflammatory bowel disease: findings from a recent survey

J Gastroenterol Hepatol. 2010 Jan;25(1):183-93. doi: 10.1111/j.1440-1746.2009.06024.x. Epub 2009 Nov 19.

Abstract

Background and aim: The prevalence and incidence of inflammatory bowel disease (IBD) differs worldwide. While the prevalence of IBD has stabilized in Europe, the USA and Japan, an increasing trend has been observed in Asia. However, there are no data on the current clinical practice for the management of IBD in the region. The present study aims to investigate the number of existing and new cases of IBD and to understand the current practice of diagnosis and treatment of IBD in different Asian countries.

Methods: A self-administered questionnaire, designed according to European and US guidelines, was distributed to IBD specialists throughout Asia. The questionnaire estimated the annual incidence of existing and new IBD cases in physicians' clinical practices and evaluated their procedures of diagnosis and preference for therapeutic treatment and maintenance treatment.

Results: Eighty-seven questionnaires were received out of the 107 distributed. In the clinical practices of these 87 respondents, there were 502 existing and 73 new cases per year for ulcerative colitis (UC) and 202 existing and 32 new cases per year for Crohn's disease (CD). Colonoscopy and histology were the most commonly used methods for the diagnosis of UC and CD, but clinical practice regarding the diagnosis of IBD varied. The treatment of choice for mild-to-moderate UC and CD was 5-aminosalicylic acid (5-ASA), which is also the preferred choice for the maintenance treatment of UC and CD.

Conclusion: Clinical practice with regards to IBD diagnosis and management varies within Asia.5-ASA is the preferred treatment and maintenance therapy for mild-to-moderate IBD.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use*
  • Asia / epidemiology
  • Attitude of Health Personnel
  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / drug therapy*
  • Colitis, Ulcerative / epidemiology
  • Colonoscopy
  • Crohn Disease / diagnosis*
  • Crohn Disease / drug therapy*
  • Crohn Disease / epidemiology
  • Diagnostic Techniques, Digestive System* / statistics & numerical data
  • Gastrointestinal Agents / therapeutic use*
  • Health Care Surveys
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Incidence
  • Mesalamine / therapeutic use
  • Perception
  • Practice Patterns, Physicians'* / statistics & numerical data
  • Prevalence
  • Severity of Illness Index
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Gastrointestinal Agents
  • Mesalamine