Natural coumarins as a novel class of neuroprotective agents

Mini Rev Med Chem. 2009 Oct;9(11):1262-71. doi: 10.2174/138955709789878141.

Abstract

Neurodegenerative disorders are a heterogeneous group of diseases and are among the most invaliding syndromes for humans. The aim of this manuscript is to review what has been reported so far in the literature about coumarins as a novel class of pharmacologically active compounds in chemoprevention and/or therapy of these diseases.

Publication types

  • Review

MeSH terms

  • Coumarins / chemistry*
  • Coumarins / pharmacology
  • Furocoumarins / chemistry
  • Furocoumarins / pharmacology
  • Humans
  • Neurodegenerative Diseases / drug therapy
  • Neuroprotective Agents / chemistry*
  • Neuroprotective Agents / pharmacology

Substances

  • 7-isopentenyloxycoumarin
  • Coumarins
  • Furocoumarins
  • Neuroprotective Agents
  • fraxetin
  • imperatorin