In July 2008, owners of seasonal camps in Vermont and Maine were exposed to large numbers of questing ticks after opening their camps for the season. Examination of collected specimens revealed that the camp in Vermont was infested with Ixodes cookei Packard, and the camp in Maine was infested with Ixodes marxi Banks. In both instances, numerous tick bites were reported by residents. Both camps were also occupied by wildlife during the off-season, primarily squirrels (Maine) and skunks (Vermont). Subsequent samples from the Vermont site were tested for the presence of Powassan encephalitis virus, though no viral activity was detected.