Complementary acupuncture treatment increases cerebral metabolism in patients with Parkinson's disease

Int J Neurosci. 2009;119(8):1190-7. doi: 10.1080/00207450802336774.

Abstract

We used positron emission tomography (PET) and the 18-flourodeoxyglucose tracer to study cerebral effects of complementary acupuncture in Parkinson's disease. Five patients received scalp-acupuncture and Madopa, while the other five had Madopa only. PET scans before and after 5 weeks of complementary acupuncture treatment show increased glucose metabolisms in parietal, temporal, occipital lobes, the thalamus, and the cerebellum in the light-diseased hemisphere, and in parietal and occipital lobes of the severe-diseased hemisphere. No changes were observed in the Madopa-only group. Acupuncture in combination with Madopa may improve cerebral glucose metabolism in Parkinson's disease.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acupuncture Therapy*
  • Aged
  • Antiparkinson Agents / therapeutic use
  • Benserazide / therapeutic use
  • Brain Chemistry / physiology*
  • Combined Modality Therapy
  • Drug Combinations
  • Energy Metabolism / physiology
  • Female
  • Fluorodeoxyglucose F18
  • Glucose / metabolism
  • Humans
  • Image Processing, Computer-Assisted
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Parkinson Disease / diagnostic imaging
  • Parkinson Disease / metabolism*
  • Parkinson Disease / therapy*
  • Positron-Emission Tomography
  • Radiopharmaceuticals

Substances

  • Antiparkinson Agents
  • Drug Combinations
  • Radiopharmaceuticals
  • benserazide, levodopa drug combination
  • Fluorodeoxyglucose F18
  • Levodopa
  • Benserazide
  • Glucose