Congenital heart disease in adults: an 8-year surgical experience in a medium-volume cardiac center

J Cardiovasc Med (Hagerstown). 2010 Mar;11(3):175-81. doi: 10.2459/JCM.0b013e328333089b.

Abstract

Objectives: We report our 8-year experience with surgery for congenital heart disease in adults in a medium-volume surgical center.

Methods: We collected data of 161 consecutive patients who underwent 230 procedures from January 1997 to December 2004. Surgical procedures were divided into two groups: repair (85.7%) and reoperation (14.3).

Results: There was only one in-hospital death (Fontan revision, in reoperation group). At a mean follow-up time of 56 +/- 30 months, overall freedom from any kind of complication is 76.5%. Cox analysis showed that incremental risk factors were preoperative cyanosis, reoperation, and length of ICU stay (hazard ratio = 4.47, 3.34 and 1.49, respectively; P < 0.001 in all), whereas decremental risk factors were preoperative New York Heart Association class 1 (hazard ratio = 0.328, P < 0.001) and surgery for 'septal defect' (hazard ratio = 0.26, P = 0.02).

Conclusion: Surgery for congenital heart disease in adults seems to be an overall well-tolerated and a low-risk treatment, with overall good mid-term clinical results.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cardiac Surgical Procedures* / adverse effects
  • Cardiac Surgical Procedures* / mortality
  • Cyanosis / etiology
  • Cyanosis / surgery
  • Female
  • Heart Defects, Congenital / complications
  • Heart Defects, Congenital / mortality
  • Heart Defects, Congenital / surgery*
  • Hospital Mortality
  • Humans
  • Italy
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Proportional Hazards Models
  • Reoperation
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Young Adult