Antibacterial and antifungal activity of a soda-lime glass containing copper nanoparticles

Nanotechnology. 2009 Dec 16;20(50):505701. doi: 10.1088/0957-4484/20/50/505701. Epub 2009 Nov 12.

Abstract

A low melting point soda-lime glass powder containing copper nanoparticles with high antibacterial (against gram-positive and gram-negative bacteria) and antifungal activity has been obtained. Sepiolite fibres containing monodispersed copper nanoparticles (d(50) approximately 30 +/- 5 nm) were used as the source of the copper nanoparticles. The observed high activity of the obtained glass powder, particularly against yeast, has been explained by considering the inhibitory synergistic effect of the Ca(2+) lixiviated from the glass on the growth of the colonies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Antifungal Agents / pharmacology*
  • Calcium Compounds / chemistry*
  • Copper / pharmacology*
  • Escherichia coli / drug effects
  • Escherichia coli / ultrastructure
  • Glass / chemistry*
  • Microbial Sensitivity Tests
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Oxides / chemistry*
  • Particle Size
  • Sodium Hydroxide / chemistry*
  • Spectrophotometry, Ultraviolet
  • X-Ray Diffraction

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Calcium Compounds
  • Oxides
  • soda lime
  • Sodium Hydroxide
  • Copper