Abstract
We report a 24-year-old male with systemic lupus erythematosus (SLE) who developed influenza virus B-associated hemophagocytic syndrome and cardiac tamponade. Although the patient's general condition improved after steroid pulse therapy and pericardiocentesis, pericardial effusion re-accumulated. Colchicine and aspirin were administered, together with prednisolone, after which no further relapses occurred. This was a rare case of severe influenza-associated hemophagocytic syndrome and steroid-resistant pericardial effusion in an SLE patient.
MeSH terms
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Anti-Inflammatory Agents / therapeutic use
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Aspirin / therapeutic use
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Colchicine / therapeutic use
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Drug Therapy, Combination
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Humans
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Influenza B virus*
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Influenza, Human / complications*
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / drug therapy
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Lupus Erythematosus, Systemic / virology
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Lymphohistiocytosis, Hemophagocytic / complications*
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Lymphohistiocytosis, Hemophagocytic / pathology
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Male
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Pericarditis / complications*
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Pericarditis / diagnostic imaging
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Pericarditis / drug therapy
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Prednisolone / therapeutic use
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Ultrasonography
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Young Adult
Substances
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Anti-Inflammatory Agents
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Prednisolone
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Aspirin
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Colchicine