Radiotherapy of malignant gliomas: comparison of volumetric single arc technique (RapidArc), dynamic intensity-modulated technique and 3D conformal technique

Radiother Oncol. 2009 Dec;93(3):593-6. doi: 10.1016/j.radonc.2009.10.002. Epub 2009 Nov 10.

Abstract

Purpose: The analysis was designed to identify the optimal radiation technique for patients with malignant glioma.

Methods: A volumetric-modulated radiation treatment technique (RapidArc), an IMRT technique and a 3D conformal technique were calculated on computed tomograms of 14 consecutive patients with malignant glioma. The treatment plans were compared with each other using dose-volume histograms.

Results: The 3D conformal technique showed a good PTV coverage, if PTV was distant to organs at risk (OAR). If PTV was nearby OAR, the 3D technique revealed a poor PTV coverage in contrast to both intensity-modulated techniques. The conventional IMRT technique showed a slightly better PTV coverage than RapidArc. The advantages of RapidArc were a shorter treatment time, less monitor units and a small V(107%).

Conclusions: If PTV is distant to OAR, the use of 3D conformal technique is sufficient. Otherwise an intensity-modulated technique should be used. RapidArc was faster than conventional IMRT and should be preferred if PTV coverage is adequate.

Publication types

  • Comparative Study

MeSH terms

  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / radiotherapy*
  • Glioma / diagnostic imaging
  • Glioma / radiotherapy*
  • Humans
  • Radiotherapy Dosage
  • Radiotherapy, Conformal*
  • Radiotherapy, Intensity-Modulated* / methods
  • Technology, Radiologic
  • Tomography, X-Ray Computed