The role of tetraspanins in the pathogenesis of infectious diseases

Microbes Infect. 2010 Feb;12(2):106-12. doi: 10.1016/j.micinf.2009.11.001. Epub 2009 Nov 5.

Abstract

Tetraspanin proteins on host cells are involved in the pathogenesis of infectious diseases at different stages. In this review, we will focus on tetraspanins expressed in the immune system and the role they play in the defense to viral, bacterial, parasitic and fungal infections.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antigens, CD / metabolism*
  • Bacteria / pathogenicity
  • Bacterial Infections / etiology
  • Bacterial Infections / immunology
  • Bacterial Infections / metabolism
  • Fungi / pathogenicity
  • Humans
  • Infections / etiology*
  • Infections / immunology
  • Infections / metabolism
  • Membrane Proteins / metabolism*
  • Parasites / pathogenicity
  • Parasitic Diseases / etiology
  • Parasitic Diseases / immunology
  • Parasitic Diseases / metabolism
  • Virus Diseases / etiology
  • Virus Diseases / immunology
  • Virus Diseases / metabolism
  • Viruses / pathogenicity

Substances

  • Antigens, CD
  • Membrane Proteins