Transgenic expression of Notch in melanocytes demonstrates RBP-Jkappa-dependent signaling

Pigment Cell Melanoma Res. 2010 Feb;23(1):134-6. doi: 10.1111/j.1755-148X.2009.00651.x. Epub 2009 Nov 6.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation / genetics
  • Cell Lineage / genetics
  • Cell Proliferation
  • Gene Expression Regulation / genetics*
  • Hair / anatomy & histology
  • Hair / metabolism
  • Immunoglobulin J Recombination Signal Sequence-Binding Protein / genetics*
  • Immunoglobulin J Recombination Signal Sequence-Binding Protein / metabolism
  • Melanocytes / cytology
  • Melanocytes / metabolism*
  • Melanoma / genetics
  • Melanoma / metabolism
  • Melanoma / physiopathology
  • Mice
  • Mice, Transgenic
  • Pigmentation / genetics
  • Receptor, Notch1 / genetics*
  • Receptor, Notch1 / metabolism
  • Receptor, Notch2 / genetics
  • Receptor, Notch2 / metabolism
  • Signal Transduction / genetics*
  • Skin Neoplasms / genetics
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / physiopathology
  • Stem Cells / cytology
  • Stem Cells / metabolism

Substances

  • Immunoglobulin J Recombination Signal Sequence-Binding Protein
  • Notch1 protein, mouse
  • Notch2 protein, mouse
  • Receptor, Notch1
  • Receptor, Notch2