[Steroids from Monascus purpureus metabolite]

Zhongguo Zhong Yao Za Zhi. 2009 Jul;34(14):1809-11.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents of Monascus purpureus metabolite.

Method: The compounds were isolated by column chromatography methods, and their structures were determined by spectroscopic methods.

Result: Eight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one (1), 3-oxo-24-methylenecycloarane (2), stigmasterol (3), 7beta-hydroxystigmasterol (4), 3beta-hydroxystigmast-5-en-7-one (5), 3beta-hydroxystigmast-5,22-dien-7-one (6), 5alpha, 8alpha-epidioxyergosta-6,22-dien-3beta-ol (7), sitosterol (8).

Conclusion: All of the compounds were isolated from this genu for the first time except compound 3 and 7.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / metabolism*
  • Monascus / chemistry*
  • Monascus / metabolism*
  • Steroids / chemistry
  • Steroids / isolation & purification
  • Steroids / metabolism*

Substances

  • Drugs, Chinese Herbal
  • Steroids