Gastrointestinal infections in the pediatric population

Curr Opin Gastroenterol. 2010 Jan;26(1):36-44. doi: 10.1097/MOG.0b013e328333d799.

Abstract

Purpose of review: To summarize the literature concerning gastrointestinal infections in the pediatric population, primarily in developed countries. Searches of MEDLINE and the Cochrane Library databases were performed in August 2009 to locate studies published in the last 18 months.

Recent findings: Several independent guidelines based on systematic reviews of the best available evidence related to rotavirus vaccination and to the management of acute gastroenteritis were recently published. Despite subtle differences, there is agreement between the scientific societies that rotavirus vaccination should be offered to all children worldwide. Likewise, there is consensus in the guidelines that rehydration therapy is the mainstay of treatment for acute gastroenteritis and should be applied promptly. For oral rehydration, a reduced osmolality oral rehydration solution should be used. Regular feeding should not be interrupted and should be carried on following initial rehydration. The use of some antiemetics and antidiarrheal drugs has been studied; however, they are generally not necessary. The use of probiotics with documented efficacy may be considered. Antibiotics should not be routinely administered to children with gastroenteritis.

Summary: This review discusses the most recent relevant guidelines related to gastrointestinal infections in children, which may facilitate provision of more standardized advice and treatment to patients by healthcare providers.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Age Distribution
  • Anti-Bacterial Agents / therapeutic use
  • Antiemetics / therapeutic use
  • Antiviral Agents / therapeutic use
  • Child
  • Child, Preschool
  • Clostridium Infections / epidemiology
  • Clostridium Infections / prevention & control
  • Clostridium Infections / therapy*
  • Evidence-Based Medicine
  • Female
  • Fluid Therapy
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / prevention & control
  • Gastroenteritis / therapy*
  • Humans
  • Incidence
  • Infant
  • Male
  • Practice Guidelines as Topic
  • Probiotics
  • Prognosis
  • Risk Assessment
  • Rotavirus Infections / epidemiology
  • Rotavirus Infections / prevention & control
  • Rotavirus Infections / therapy*
  • Rotavirus Vaccines / administration & dosage
  • Sex Distribution
  • Treatment Outcome
  • Vaccination / methods

Substances

  • Anti-Bacterial Agents
  • Antiemetics
  • Antiviral Agents
  • Rotavirus Vaccines