With the aim of evaluating serum cholesterol and triglyceride concentrations in Lithuanian wild boar and Lithuanian pig breeds, twelve gilts from three genotype groups were used in the experiment. Only the concentration of high-density lipoprotein (HDL) was significantly higher in the serum of wild boar than in serum of domestic pig breeds (P < 0.05). Factor loadings of the principal components (PCs) revealed that lipoproteins were positively related in PC1 for wild boars but associations between lipoproteins of domestic pigs varied differently in PC1 and PC2. Cluster analysis showed a greater distance between wild boar and domestic pigs than that between two domestic pig breeds.