Microbial transformation of a monoterpene, geraniol, by the marine-derived fungus Hypocrea sp

J Microbiol Biotechnol. 2009 Oct;19(10):1150-2.

Abstract

Geraniol (1) is the biogenetic precursor of a number of monoterpenes. We tested various marine-derived microorganisms to determine their ability to biotransform 1. Only Hypocrea sp. was capable of transforming 1 into its oxidized derivative, 1,7-dihydroxy-3,7-dimethyl-(E)-oct- 2-ene (2). The structure of the metabolite obtained was assigned on the basis of detailed spectroscopic data analyses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acyclic Monoterpenes
  • Biotransformation
  • Hypocrea / chemistry
  • Hypocrea / isolation & purification
  • Hypocrea / metabolism*
  • Monoterpenes / chemistry
  • Monoterpenes / metabolism*
  • Seawater / microbiology*
  • Terpenes / chemistry
  • Terpenes / metabolism*

Substances

  • Acyclic Monoterpenes
  • Monoterpenes
  • Terpenes
  • geraniol