Abstract
Bechet's disease (BD) is an inflammatory, multi systemic disease with spontaneous remissions and relapses similar to various autoimmune diseases. BD leads to organ damage, including the eyes, skin, joints, etc., which produces various clinical manifestations. The central histopathologic characteristic is systemic vasculitis with perivascular inflammatory infiltrates. The etiopathogenesis is unknown, although immunological abnormalities, possibly induced by susceptible microbiological pathogens, have been postulated.
Copyright 2009. Published by Elsevier B.V.
MeSH terms
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Adrenal Cortex Hormones / therapeutic use
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Behcet Syndrome / diagnosis*
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Behcet Syndrome / drug therapy
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Behcet Syndrome / epidemiology
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Behcet Syndrome / etiology*
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Behcet Syndrome / physiopathology*
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Diagnosis, Differential
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Erythema
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Genetic Predisposition to Disease
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HLA-B Antigens / genetics
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HLA-B51 Antigen
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Humans
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Middle East
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Peptidyl-Dipeptidase A / genetics
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Polymorphism, Genetic
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Prothrombin / genetics
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Systemic Vasculitis
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Thrombosis
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Tumor Necrosis Factor-alpha / genetics
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Ulcer
Substances
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Adrenal Cortex Hormones
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HLA-B Antigens
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HLA-B51 Antigen
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Tumor Necrosis Factor-alpha
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Prothrombin
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ACE protein, human
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Peptidyl-Dipeptidase A