The MPEG monophosphate ester: synthesis and characterization

J Biomater Sci Polym Ed. 2009;20(14):2103-16. doi: 10.1163/156856208X400483.

Abstract

Methods of preparation of the phosphoric ester of monomethyl ether of poly(ethylene glycol) (MPEG-P) from MPEG (M(n) = 550 and 2000) and phosphoric acid (P), or its derivatives - pyrophosphoric acid (PY), polyphosphoric acid (PP) and POCl(3)- are described and compared. MPEG-P was isolated in a pure state (no detectable impurities) and characterized.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Esters / chemical synthesis*
  • Esters / chemistry*
  • Magnetic Resonance Spectroscopy
  • Phosphoric Acids / chemistry
  • Polyethylene Glycols / chemistry
  • Polymers / chemistry

Substances

  • Esters
  • Phosphoric Acids
  • Polymers
  • Polyethylene Glycols
  • polyphosphoric acid
  • monomethoxypolyethylene glycol