[Studies on the chemical constituents of Epimedium brevicornum]

Zhong Yao Cai. 2009 Jul;32(7):1051-3.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents of Epimedium breviconum.

Methods: Compounds were purificated with various chromatographic techniques such as silica vacuum liquid chromatography and Sephadex LH-20 column chromatography. Their structures were elucidated by physico-chemical methods and spectral analysis.

Results: Ten compounds were obtained and indentified as (7R, 8S) 4,9-dihydroxyl-3,3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9'-O-alpha-L-rhamnopyranoside (1), (7R, 8S, 8' R) 4, 4', 8', 9-tetrahydroxyl-3, 3'-dimethyoxyl-7, 9'-monoepoxylignan (2), (+)-cycloolivil (3), (3, 5, 7, 4')-tetrahydroxyl-8-isopentene group flavonoids-3-O-alpha-L-rhamnopyranoside (4), beta-sitosterol (5), p-hydroxybenzaldehyde (6), succinic acid (7) and p-hydroxyphenethyl (8).

Conclusions: Compound 1 is isolated from this genus for the first time. Compounds 2,3,5 -8 are isolated from the plant for the first time.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2-Hydroxyphenethylamine
  • Benzaldehydes / chemistry
  • Benzaldehydes / isolation & purification*
  • Epimedium / chemistry*
  • Lignans / chemistry
  • Lignans / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Monosaccharides / chemistry
  • Monosaccharides / isolation & purification
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification*
  • Succinic Acid / chemistry
  • Succinic Acid / isolation & purification

Substances

  • (7S,8R)-4,9'-dihydroxyl-3, 3'-dimethyoxyl-7, 8-dihydrobenzofunan-1'-propanolneolignan-9-O-alpha- L-rhamnopyranoside
  • Benzaldehydes
  • Lignans
  • Monosaccharides
  • Phenols
  • Sitosterols
  • cycloolivil
  • gamma-sitosterol
  • 2-Hydroxyphenethylamine
  • Succinic Acid
  • 4-hydroxybenzaldehyde