New terpenoids from the soft corals Sinularia capillosa and Nephthea chabroli

Shi-Yie Cheng; Ki-Jhih Huang; Shang-Kwei Wang; Zhi-Horng Wen; Chi-Hsin Hsu; Chang-Feng Dai; Chang-Yih Duh

doi:10.1021/ol901864d

New terpenoids from the soft corals Sinularia capillosa and Nephthea chabroli

Org Lett. 2009 Nov 5;11(21):4830-3. doi: 10.1021/ol901864d.

Authors

Shi-Yie Cheng¹, Ki-Jhih Huang, Shang-Kwei Wang, Zhi-Horng Wen, Chi-Hsin Hsu, Chang-Feng Dai, Chang-Yih Duh

Affiliation

¹ Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung, Taiwan.

PMID: 19863144
DOI: 10.1021/ol901864d

Abstract

Two new terpenoids, capillosanol (1) and chabranol (2), possessing unprecedented terpenoid skeletons, were isolated from the soft corals Sinularia capillosa and Nephthea chabroli, respectively. The structures of 1 and 2 were elucidated through extensive spectroscopic analyses. The cytotoxicities of these compounds were tested in vitro.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anthozoa / chemistry*
Antineoplastic Agents / chemistry
Antineoplastic Agents / isolation & purification*
Antineoplastic Agents / pharmacology
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Terpenes / chemistry
Terpenes / isolation & purification*
Terpenes / pharmacology

Substances

Antineoplastic Agents
Terpenes
capillosanol
chabranol