Objectives: To summarize current excellent research in the field of medical sensor, signal and imaging informatics.
Method: Synopsis of the articles selected for the IMIA (International Medical Informatics Association) Yearbook 2009.
Results: Current research in the field of sensors, signal, and imaging informatics is characterized by theoretically sound techniques and evaluations with focus in imaging informatics.
Conclusions: The best paper selection of articles on sensors, signal, and imaging informatics shows examples of excellent research on methods concerning theoretically sound original development in this field. Imaging and particularly multi-dimensional imaging has had in 2008 by far the largest number of publications compared to signals and sensors.