Abstract
Proof has at last been provided that idiopathic membranous nephropathy is caused by autoantibodies to proteins expressed by podocytes. The discovery that autoantibodies to the M-type secretory phospholipase A2 receptor were present in most individuals affected by the condition opens a new era for the management of membranous nephropathy.
Publication types
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News
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Research Support, Non-U.S. Gov't
MeSH terms
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Autoantibodies / immunology*
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Glomerulonephritis, Membranous / immunology*
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Glomerulonephritis, Membranous / pathology
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Glomerulonephritis, Membranous / physiopathology*
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Humans
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Nephrotic Syndrome / immunology*
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Nephrotic Syndrome / pathology
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Nephrotic Syndrome / physiopathology*