Two new triterpenoid isomers from Nerium oleander leaves

Bina S Siddiqui; Nasima Khatoon; Sabira Begum; Saima A Durrani

doi:10.1080/14786410802573958

Two new triterpenoid isomers from Nerium oleander leaves

Nat Prod Res. 2009;23(17):1603-8. doi: 10.1080/14786410802573958.

Authors

Bina S Siddiqui¹, Nasima Khatoon, Sabira Begum, Saima A Durrani

Affiliation

¹ HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan. bina@khi.comsats.net.pk

PMID: 19851926
DOI: 10.1080/14786410802573958

Abstract

Two new triterpenoid isomers alpha-neriursate (1) and beta-neriursate (2) have been isolated from the fresh, uncrushed leaves of Nerium oleander and their structures elucidated as 3alpha-acetophenoxy-urs-12-en-28-oic acid and 3beta-acetophenoxy-urs-12-en-28-oic acid, respectively. The structure elucidation is based on spectroscopic methods, including 1D ((1)H NMR, (13)C NMR) and 2D ((1)H-(1)H COSY, NOESY, HMQC, HMBC and J-resolved) NMR data and chemical transformation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Magnetic Resonance Spectroscopy
Molecular Structure
Nerium / chemistry*
Plant Extracts / chemistry*
Plant Leaves / chemistry*
Triterpenes / chemistry*
Triterpenes / isolation & purification

Substances

Plant Extracts
Triterpenes