Abstract
The exine coatings of spores can be used to encapsulate drug molecules. We have demonstrated that these microcapsules can be filled with a commercial gadolinium(III) MRI contrast agent (in this proof of concept study Gd-DTPA-BMA was used) which is slowly released in plasma due to enzymatic digestion of the capsule.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biopolymers / chemistry*
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Carotenoids / chemistry*
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Contrast Media / chemistry*
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Drug Carriers / chemistry*
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Gadolinium DTPA / blood
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Gadolinium DTPA / chemistry*
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Magnetic Resonance Imaging*
Substances
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Biopolymers
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Contrast Media
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Drug Carriers
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sporopollenin
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Carotenoids
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Gadolinium DTPA