[Usefulness of hyperbaric oxygen in the treatment of radionecrosis and symptomatic brain edema after LINAC radiosurgery]

Neurocirugia (Astur). 2009 Oct;20(5):449-53.
[Article in Spanish]

Abstract

Radionecrosis with brain edema is a complication of radiosurgery. Three female patients harbouring a frontal pole, petrous and parasagital parietoocipital meningiomas respectively who had been treated with LINAC radiosurgery are presented. Those patients developed, between two and eight months later, a severe symptomatic radionecrosis with a huge brain edema resistant to the usual steroid therapy. Only after 40 sessions of hyperbaric oxygen, a good remission of the lesions was obtained. There are few cases reported in the literature with such a good outcome. Consequentely, this therapy must be taken into account to treat this type of radiosurgical complication before considering surgery.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Brain Damage, Chronic / etiology
  • Brain Damage, Chronic / prevention & control
  • Brain Edema / etiology
  • Brain Edema / pathology
  • Brain Edema / therapy*
  • Brain Injuries / etiology
  • Brain Injuries / pathology
  • Brain Injuries / therapy*
  • Cerebellar Neoplasms / surgery
  • Cerebellopontine Angle / pathology
  • Cerebellopontine Angle / radiation effects
  • Endothelium, Vascular / pathology
  • Endothelium, Vascular / radiation effects
  • Female
  • Humans
  • Hyperbaric Oxygenation*
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / surgery
  • Meningioma / surgery
  • Middle Aged
  • Necrosis
  • Parietal Lobe / pathology
  • Parietal Lobe / radiation effects
  • Radiation Injuries / etiology
  • Radiation Injuries / pathology
  • Radiation Injuries / therapy*
  • Radiosurgery / adverse effects*
  • Treatment Outcome