Necrobiotic xanthogranuloma of the parotid gland

J Laryngol Otol. 2010 May;124(5):569-71. doi: 10.1017/S0022215109991563. Epub 2009 Oct 14.

Abstract

Objectives: To highlight the first reported case of necrobiotic xanthogranuloma of the parotid gland. We also review the clinical presentations and treatments for this rare condition.

Method: Case report and review of necrobiotic xanthogranuloma.

Results: A 48-year-old man presented with a right parotid mass. Fine needle aspiration cytology was suggestive of Warthin's tumour, for which the patient underwent a subtotal parotidectomy. The final histopathological diagnosis was necrobiotic xanthogranuloma.

Conclusions: Necrobiotic xanthogranuloma may clinically mimic commoner tumours such as Warthin's tumour. Once diagnosed, the clinician should be wary of extracutaneous manifestations and paraproteinaemias. Because of the variability of presentation, there is no consensus on the best treatment for necrobiotic xanthogranuloma, which may include surgery, chemotherapy, interferon, plasmapheresis and radiation therapy.

Publication types

  • Case Reports

MeSH terms

  • Granuloma / pathology*
  • Granuloma / surgery
  • Humans
  • Male
  • Middle Aged
  • Parotid Diseases / pathology*
  • Parotid Diseases / surgery
  • Xanthomatosis / pathology*
  • Xanthomatosis / surgery