Abstract
Treatment with cinacalcet and intravenous bisphosphonate has improved the previously often fatal prognosis of parathyroid cancer. We report two cases, of which one did not react to treatment and died within a short time-frame. In the other case, cinacalcet controlled serum calcium during a prolonged time period despite metastases. However, increasing doses of cinacalcet combined with more frequent intravenous bisphosphonate were necessary.
MeSH terms
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Aged
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Bone Density Conservation Agents / administration & dosage
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Bone Density Conservation Agents / therapeutic use
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Calcium / blood*
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Cinacalcet
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Diphosphonates / administration & dosage
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Diphosphonates / therapeutic use
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Fatal Outcome
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Female
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Humans
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Imidazoles / administration & dosage
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Imidazoles / therapeutic use
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Male
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Naphthalenes / administration & dosage
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Naphthalenes / therapeutic use*
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Parathyroid Neoplasms / blood
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Parathyroid Neoplasms / drug therapy*
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Prognosis
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Treatment Outcome
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Zoledronic Acid
Substances
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Bone Density Conservation Agents
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Diphosphonates
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Imidazoles
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Naphthalenes
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Zoledronic Acid
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Calcium
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Cinacalcet