[Experimental cryptorchism in the Wistar rat]

Cir Pediatr. 1990 Jul;3(3):97-102.
[Article in Spanish]

Abstract

Experimental cryptorchidism was performed on Wistar rats, fixing the left testicle into the peritoneum for a month. Animals under study (84) were divided into four groups: control, control treated with hCG, cryptorchid and cryptorchid treated with hCG. Cryptorchid testes were biopsied at three, five and eight months and all were excised at 12 months. Cellular counts on spermatogonia, young and late spermatocytes, Sertoli cells and vacuolized Sertoli cells, together with the slough tubular and germinal cell percentage and the tubular diameter, let us affirm by means statistical studies (ANOVA, Chi square) that a testes recovering is already shown at the age of five months, although this recovering still differs from the one shown in the control groups.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Animals
  • Biopsy
  • Chorionic Gonadotropin / administration & dosage
  • Cryptorchidism / etiology*
  • Cryptorchidism / pathology
  • Disease Models, Animal*
  • Male
  • Rats
  • Rats, Inbred Strains*
  • Sertoli Cells / drug effects
  • Sertoli Cells / pathology
  • Spermatogenesis / drug effects
  • Testis / drug effects
  • Testis / pathology
  • Time Factors

Substances

  • Chorionic Gonadotropin