New strategies in molecular genetic studies of X-linked retinitis pigmentosa

Eye (Lond). 1990:4 ( Pt 5):737-42. doi: 10.1038/eye.1990.105.

Abstract

New techniques developed in the past few years are being used to isolate the genes responsible for X-linked retinitis pigmentosa. The use of hypervariable probes in linkage, the construction of genetic and physical maps, and the search for putative gene sequences of interest are described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blotting, Southern
  • DNA / analysis
  • DNA Probes
  • Genetic Linkage*
  • Genetic Markers
  • Humans
  • Pedigree
  • Polymorphism, Restriction Fragment Length
  • Retinitis Pigmentosa / genetics*
  • X Chromosome*

Substances

  • DNA Probes
  • Genetic Markers
  • DNA