Histological variants of colon carcinoma depending upon the quantity of endocrine cells are distinguished on the basis of 66 malignant epithelial colon tumours morphological investigation. Special emphasis was made on the characteristics of the endocrine cell carcinoma, combined tumours with a combination of glandular and endocrine components, and amphicrin neoplasms. A trabecular-glandular variant of endocrine cell carcinoma is found to be predominant in the colon. The criteria are suggested for the identification of endocrine-cell tumours.