Abstract
Anergic B cells are autoreactive and are present in the periphery in an unresponsive state. Here we will discuss the difference in B cell receptor signaling between anergic B cells, chronically stimulated by autoantigen, and naïve B cell encountering antigen.
MeSH terms
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Animals
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B-Lymphocytes / immunology*
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Clonal Anergy*
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Humans
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Intracellular Signaling Peptides and Proteins / metabolism
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Lymphocyte Activation*
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Protein-Tyrosine Kinases / metabolism
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Receptor Cross-Talk / immunology
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Receptors, Antigen, B-Cell / immunology*
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Signal Transduction / immunology
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Syk Kinase
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src-Family Kinases / metabolism
Substances
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Intracellular Signaling Peptides and Proteins
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Receptors, Antigen, B-Cell
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Protein-Tyrosine Kinases
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SYK protein, human
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Syk Kinase
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lyn protein-tyrosine kinase
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src-Family Kinases