Objective: To study the clinical characteristics and significance of blood eosinophilia in lung cancer.
Methods: A case of lung cancer with eosinophilia in the peripheral blood was analyzed, and the related literature was reviewed.
Results: A 80-year-old male patient presented with chest pain was admitted to this hospital. Chest CT scan showed a cavity in the right upper lung. Peripheral blood leukocyte count was 2.15 x 10(9)/L, of which 16.9% was mature eosinophils. Histological examination of the biopsy specimens obtained under CT guidance confirmed the diagnosis of lung squamous cell carcinoma. There was also evidence of metastasis to the bones.
Conclusions: Paraneoplastic eosinophilia is uncommon in solid malignancies and indicative of tumor dissemination with generally poor prognosis.