Abstract
Drug-induced neutropenia (DIN), particularly that in which antibiotic-dependent antineutrophil antibodies have been detected, is a rare disorder. We report the case of a child with pneumococcal pneumonia, who experienced severe neutropenia during various antibiotic treatments. We detected 4 kinds (cefotaxim, augmentin, vancomycin, and tobramycin) of antibiotic-dependent antineutrophil antibodies by using the mixed passive hemagglutination assay (MPHA) technique with this child.
Keywords:
Anti-Bacterial Agents; Antineutrophil Antibody; Neutropenia.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Antibodies, Antineutrophil Cytoplasmic / blood*
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Antibodies, Antineutrophil Cytoplasmic / immunology
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Autoantibodies / blood
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Autoantibodies / immunology
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Drug Therapy, Combination
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Humans
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Infant
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Male
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Neutropenia / chemically induced
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Neutropenia / diagnosis*
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Pneumonia, Pneumococcal / complications
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Pneumonia, Pneumococcal / drug therapy*
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Tomography, X-Ray Computed
Substances
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Anti-Bacterial Agents
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Antibodies, Antineutrophil Cytoplasmic
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Autoantibodies