A study of triggers of migraine in India

Pain Med. 2010 Jan;11(1):44-7. doi: 10.1111/j.1526-4637.2009.00725.x. Epub 2009 Sep 29.

Abstract

Objective: To evaluate the migraine triggers in consecutive patients and correlate these with demographic and clinical variables.

Design: A prospective study.

Setting: Tertiary care teaching hospital.

Subject and methods: A total of 182 patients with migraine were included whose age ranged between 14 to 58 years and 131 were females. Duration of migraine ranged between 6 and 260 months. Endogenous and exogenous migraine triggers were inquired using a questionnaire. Severity of migraine, associated symptoms, and functional disability were recorded. Presence of trigger was correlated with various demographic and clinical variables.

Results: Migraine triggers were present in 160 (87.9%) patients and included emotional stress in 70%, fasting in 46.3%, physical exhaustion or traveling in 52.5%, sleep deprivation in 44.4%, menstruation in 12.8%, and weather changes in 10.1% patients. Multiple triggers (>2) were present in 34.4% patients.

Conclusion: The triggers in the Indian migraine patients are similar to other populations but for dietary factors.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Diet
  • Disability Evaluation
  • Eating
  • Female
  • Humans
  • Ibuprofen / therapeutic use
  • India / epidemiology
  • Male
  • Middle Aged
  • Migraine Disorders / drug therapy
  • Migraine Disorders / epidemiology*
  • Migraine Disorders / etiology*
  • Pain Measurement
  • Physical Exertion / physiology
  • Prognosis
  • Prospective Studies
  • Serotonin Receptor Agonists / therapeutic use
  • Sleep Deprivation
  • Stress, Psychological / complications
  • Triazoles / therapeutic use
  • Tryptamines / therapeutic use
  • Weather
  • Young Adult

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Serotonin Receptor Agonists
  • Triazoles
  • Tryptamines
  • rizatriptan
  • Ibuprofen