A fluorescence lifetime imaging scanning confocal endomicroscope

J Biophotonics. 2010 Jan;3(1-2):103-7. doi: 10.1002/jbio.200910065.

Abstract

We describe a fluorescence lifetime imaging endomicroscope employing a fibre bundle probe and time correlated single photon counting. Preliminary images of stained pollen grains, eGFP-labelled cells exhibiting Förster resonant energy transfer and tissue autofluorescence are presented.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • COS Cells
  • Chlorocebus aethiops
  • Endoscopes*
  • Endoscopy / methods*
  • Fluorescence
  • Green Fluorescent Proteins / metabolism
  • Microscopy, Confocal / instrumentation*
  • Microscopy, Fluorescence / instrumentation*
  • Photons
  • Pollen
  • Rats
  • Tendons / anatomy & histology
  • Time Factors

Substances

  • enhanced green fluorescent protein
  • Green Fluorescent Proteins