A delicate balance between sp2 and sp3 C-H bond activation: a Pt(II) complex with a dual agostic interaction

Sarah H Crosby; Guy J Clarkson; Jonathan P Rourke

doi:10.1021/ja905046n

A delicate balance between sp2 and sp3 C-H bond activation: a Pt(II) complex with a dual agostic interaction

J Am Chem Soc. 2009 Oct 14;131(40):14142-3. doi: 10.1021/ja905046n.

Authors

Sarah H Crosby¹, Guy J Clarkson, Jonathan P Rourke

Affiliation

¹ Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK.

PMID: 19764750
DOI: 10.1021/ja905046n

Abstract

2-tert-Butyl-6-(4-fluorophenyl)pyridine reacts with K(2)PtCl(4) via the activation of an sp(2) C-H bond to give a cyclometalated complex that contains a bifurcated agostic interaction. Rearrangement of this complex results in the activation of an sp(3) C-H bond, and reaction eventually leads to a doubly cyclometalated complex where both sp(2) and sp(3) C-H bonds have been activated. Deuterium exchange studies show that a delicate balance exists between the two cyclometalations.