Band assignment in hemoglobin porphyrin ring spectrum: using four-orbital model of Gouterman

Protein Pept Lett. 2010 Apr;17(4):473-9. doi: 10.2174/092986610790963645.

Abstract

Band assignment for oxy, deoxy and methemoglobin using orbital promotion is crucial to understanding inter-relation of electronic transitions. Spectral changes may be correlated with conformational alteratiions. Conformational changes of hemoglobin were interpreted using four-orbital model of Gouterman. Our results indicated that Goutherman model can predict the predominant conformations of hemoglobin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dithionite / chemistry
  • Ferricyanides / chemistry
  • Hemoglobins / chemistry*
  • Hydrogen-Ion Concentration
  • Iron / chemistry
  • Iron / metabolism
  • Oxidation-Reduction
  • Oxyhemoglobins / chemistry*
  • Porphyrins / chemistry*
  • Porphyrins / metabolism
  • Sodium Dodecyl Sulfate / chemistry
  • Spectrophotometry / methods*

Substances

  • Ferricyanides
  • Hemoglobins
  • Oxyhemoglobins
  • Porphyrins
  • hexacyanoferrate III
  • Dithionite
  • Sodium Dodecyl Sulfate
  • deoxyhemoglobin
  • Iron