Tn6060, a transposon from a genomic island in a Pseudomonas aeruginosa clinical isolate that includes two class 1 integrons

Antimicrob Agents Chemother. 2009 Dec;53(12):5294-6. doi: 10.1128/AAC.00687-09. Epub 2009 Sep 14.

Abstract

A 25,441-bp transposon was recovered from a Pseudomonas aeruginosa clinical isolate. While the transposition module was >99% identical to sequence of Tn1403, the element had been subject to rearrangements, with two In70.2-like class 1 integrons inserted into it in an unusual "tail-to-tail" configuration. One cassette array was the same as that in In70.2; however, the second was different, generating a transposon that collectively includes six resistance cassettes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • DNA Transposable Elements / genetics*
  • Genomic Islands / genetics*
  • Humans
  • Integrons / genetics*
  • Models, Genetic
  • Molecular Sequence Data
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / isolation & purification

Substances

  • DNA Transposable Elements

Associated data

  • GENBANK/GQ161847