A cascade cycloaddition strategy leading to the total synthesis of (-)-FR182877

Angew Chem Int Ed Engl. 2002 May 17;41(10):1787-90. doi: 10.1002/1521-3773(20020517)41:10<1787::aid-anie1787>3.0.co;2-v.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Antineoplastic Agents / chemical synthesis*
  • Antineoplastic Agents / chemistry
  • Chemistry, Organic / methods
  • Chemistry, Pharmaceutical / methods*
  • Drug Design
  • Models, Chemical
  • Models, Molecular
  • Molecular Conformation
  • Polycyclic Compounds / chemical synthesis*
  • Polycyclic Compounds / chemistry
  • Stereoisomerism
  • Streptomyces / metabolism

Substances

  • Antineoplastic Agents
  • FR 182877
  • Polycyclic Compounds