A single slow electron triggers the loss of both chlorine atoms from the anticancer drug cisplatin: implications for chemoradiation therapy

Angew Chem Int Ed Engl. 2009;48(42):7904-7. doi: 10.1002/anie.200903874.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / radiation effects*
  • Chlorine / chemistry*
  • Cisplatin / chemistry
  • Cisplatin / radiation effects*
  • DNA Adducts / chemistry
  • DNA Replication / drug effects
  • DNA Replication / radiation effects
  • Electron Transport / radiation effects
  • Electrons*
  • Humans
  • Neoplasms / drug therapy
  • Neoplasms / radiotherapy
  • Radiation-Sensitizing Agents / chemistry
  • Radiation-Sensitizing Agents / radiation effects*

Substances

  • Antineoplastic Agents
  • DNA Adducts
  • Radiation-Sensitizing Agents
  • Chlorine
  • Cisplatin