In this chapter we consider a distinct example of the link between biology and technology, with particular reference to the brain. We look at the example of a brain cultured in the laboratory which is then linked to a physical robot body. The overall entity therefore consists of a physical robot body controlled by a purely biological brain. The entire system provides a wonderful base for the study of the fundamental features of diseases such as strokes and Alzheimer's disease, as well as allowing for a basic investigation into the mechanisms for neural signal transfer.