A locally acquired falciparum malaria via nosocomial transmission in Korea

Korean J Parasitol. 2009 Sep;47(3):269-73. doi: 10.3347/kjp.2009.47.3.269. Epub 2009 Aug 28.

Abstract

A 57-year old man who was admitted to an emergency room of a tertiary hospital with hemoptysis developed malarial fever 19 days later and then died from severe falciparum malaria 2 days later. He had not traveled outside of Korea for over 30 years. Through intensive interviews and epidemiological surveys, we found that a foreign patient with a recent history of travel to Africa was transferred to the same hospital with severe falciparum malaria. We confirmed through molecular genotyping of the MSP-1 gene that Plasmodium falciparum genotypes of the 2 patients were identical. It is suggested that a breach of standard infection control precautions resulted in this P. falciparum transmission between 2 patients in a hospital environment. This is the first report of a nosocomial transmission of falciparum malaria in Korea.

Keywords: Plasmodium falciparum; malaria; nosocomial transmission.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa
  • Amino Acid Sequence
  • Animals
  • Cross Infection / parasitology
  • Cross Infection / transmission*
  • Fatal Outcome
  • Humans
  • Korea
  • Malaria, Falciparum / parasitology
  • Malaria, Falciparum / transmission*
  • Male
  • Merozoite Surface Protein 1 / chemistry
  • Merozoite Surface Protein 1 / genetics
  • Middle Aged
  • Molecular Sequence Data
  • Plasmodium falciparum / chemistry
  • Plasmodium falciparum / genetics
  • Plasmodium falciparum / isolation & purification*
  • Protozoan Proteins / chemistry
  • Protozoan Proteins / genetics
  • Sequence Alignment
  • Travel

Substances

  • Merozoite Surface Protein 1
  • Protozoan Proteins