Splenic abscess: a review of 22 cases in a single institution

Eur J Intern Med. 2009 Sep;20(5):537-9. doi: 10.1016/j.ejim.2009.04.009. Epub 2009 Jun 6.

Abstract

Purpose: To describe the demographics, clinical features, etiology, imaging findings, bacteriologic profile, treatment and outcome in patients presenting splenic abscess in a European tertiary hospital.

Methods: Review of the medical charts of patients in whom splenic abscess was diagnosed at a tertiary hospital in Madrid (Spain) within a nine-year period.

Results: Twenty-two cases (13 males, 9 females) were found. Mycobacterium tuberculosis was the most frequent causative microorganism, accounting for 8 cases, and immunosuppression the main predisposing factor (in 63.6% of the patients). Symptoms were quite unspecific, leading to a long, median time until diagnosis (17 days). The overall mortality rate was 18.2% and it was 25% in patients with tuberculosis and 14.28% in patients with other causes of splenic abscesses (p=0.6).

Conclusions: Immunosuppressed states are the predisposing condition for splenic abscess in almost two thirds of the patients. We found a higher percentage of M. tuberculosis than that previously reported in the English literature.

MeSH terms

  • Abscess / diagnosis*
  • Abscess / microbiology*
  • Abscess / therapy
  • Adolescent
  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Candidiasis / diagnosis
  • Candidiasis / therapy
  • Child
  • Child, Preschool
  • Cohort Studies
  • Drainage
  • Female
  • Gram-Negative Bacterial Infections / diagnosis
  • Gram-Negative Bacterial Infections / therapy*
  • Gram-Positive Bacterial Infections / diagnosis
  • Gram-Positive Bacterial Infections / therapy*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Spain
  • Splenic Diseases / diagnosis*
  • Splenic Diseases / microbiology*
  • Splenic Diseases / therapy
  • Young Adult

Substances

  • Anti-Bacterial Agents