Cerebral aspergillosis caused by Aspergillus granulosus

J Clin Microbiol. 2009 Oct;47(10):3386-90. doi: 10.1128/JCM.00588-09. Epub 2009 Aug 26.

Abstract

Disseminated disease by Aspergillus granulosus has been reported only once previously in a cardiac transplant recipient. We report a fatal central nervous system infection in a lung transplant recipient. Key features of this species in the section Usti include growth at 37 degrees C and large, randomly spaced aggregates of variably shaped Hülle cells.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Antifungal Agents / pharmacology
  • Aspergillus / cytology
  • Aspergillus / genetics
  • Aspergillus / isolation & purification*
  • Cerebrum / microbiology
  • Cerebrum / pathology
  • DNA, Fungal / chemistry
  • DNA, Fungal / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • DNA, Ribosomal Spacer / chemistry
  • DNA, Ribosomal Spacer / genetics
  • Fatal Outcome
  • Genes, rRNA
  • Humans
  • Immunocompromised Host
  • Lung Transplantation / adverse effects
  • Male
  • Microbial Sensitivity Tests
  • Microscopy
  • Molecular Sequence Data
  • Neuroaspergillosis / diagnosis*
  • Neuroaspergillosis / microbiology
  • RNA, Fungal / genetics
  • RNA, Ribosomal, 28S / genetics
  • Sequence Analysis, DNA

Substances

  • Antifungal Agents
  • DNA, Fungal
  • DNA, Ribosomal
  • DNA, Ribosomal Spacer
  • RNA, Fungal
  • RNA, Ribosomal, 28S

Associated data

  • GENBANK/FJ771045
  • GENBANK/FJ771046
  • GENBANK/FJ771047