International clones of Klebsiella pneumoniae and Escherichia coli with extended-spectrum beta-lactamases in a Czech hospital

J Clin Microbiol. 2009 Oct;47(10):3353-7. doi: 10.1128/JCM.00901-09. Epub 2009 Aug 26.

Abstract

A 2-month survey of extended-spectrum beta-lactamase (ESBL) producers was performed in a Czech hospital. Klebsiella pneumoniae produced SHV-2, -5, or -12, Escherichia coli produced CTX-M-9 or -15, and other species produced TEM-92 or -132. All K. pneumoniae and E. coli isolates belonged to sequence types (STs) or clonal complexes (CCs) spread across the world (K. pneumoniae clonal complex 11 [CC11], CC14, and sequence type 101 [ST101] and E. coli CC31, CC73, CC131, and CC405) and carried various plasmids (mainly with A/C- and FII-type replicons).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Typing Techniques
  • Czech Republic
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Enterobacteriaceae Infections / microbiology*
  • Escherichia coli / classification*
  • Escherichia coli / enzymology*
  • Escherichia coli / isolation & purification
  • Genotype
  • Hospitals
  • Humans
  • Klebsiella pneumoniae / classification*
  • Klebsiella pneumoniae / enzymology*
  • Klebsiella pneumoniae / isolation & purification
  • Microbial Sensitivity Tests
  • Plasmids
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / chemistry
  • beta-Lactamases / genetics
  • beta-Lactamases / metabolism

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • beta-Lactamases