Abstract
MicroRNAs (miRNAs) are small RNA strands (20-25 nucleotides) that regulate gene expression by translational repression as well as by messenger RNA degradation. This review will examine the application and function of miRNAs in immune cell development and differentiation.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Animals
-
B-Lymphocytes / cytology
-
B-Lymphocytes / immunology
-
Cell Differentiation
-
Gene Expression
-
Hematopoiesis / genetics
-
Hematopoiesis / immunology
-
Humans
-
Leukemia, Lymphocytic, Chronic, B-Cell / genetics
-
Leukemia, Lymphocytic, Chronic, B-Cell / immunology
-
Lymphoma, T-Cell / genetics
-
Lymphoma, T-Cell / immunology
-
MicroRNAs / genetics
-
MicroRNAs / immunology*
-
Monocytes / cytology
-
Monocytes / immunology
-
Neoplasms / genetics
-
Neoplasms / immunology
-
RNA, Neoplasm / genetics
-
RNA, Neoplasm / immunology
-
Ribonuclease III / metabolism
-
T-Lymphocytes / cytology
-
T-Lymphocytes / immunology
Substances
-
MicroRNAs
-
RNA, Neoplasm
-
Ribonuclease III