The purpose of the present study was to examine whether exposure to the suffering of unknown persons, as an inevitable part of life, influences cognitions about health. Our assumption was that exposure to suffering affects cognitions in a negative way, as well as this influence being exerted directly and through negative mood. Eighty-nine participants were randomly assigned to two groups. The experimental group was exposed to a series of photos presenting situations of human suffering, whereas the control group was exposed to a series of photos showing relaxing situations. Participants in the experimental group reported higher health anxiety and health value, and lower internal health locus of control, in comparison to the control group. No differences were found in self-rated health. Exposure to suffering affected cognitions directly and through decrease in positive mood. It seems that an 'in vitro' exposure to human suffering activates a cognitive and emotional reaction, which affects evaluations about self and personal well-being.