Image quality and stability of image-guided radiotherapy (IGRT) devices: A comparative study

Radiother Oncol. 2009 Oct;93(1):1-7. doi: 10.1016/j.radonc.2009.07.012. Epub 2009 Aug 18.

Abstract

Introduction: Our aim was to implement standards for quality assurance of IGRT devices used in our department and to compare their performances with that of a CT simulator.

Materials and methods: We investigated image quality parameters for three devices over a period of 16months. A multislice CT was used as a benchmark and results related to noise, spatial resolution, low contrast visibility (LCV) and uniformity were compared with a cone beam CT (CBCT) at a linac and simulator.

Results: All devices performed well in terms of LCV and, in fact, exceeded vendor specifications. MTF was comparable between CT and linac CBCT. Integral nonuniformity was, on average, 0.002 for the CT and 0.006 for the linac CBCT. Uniformity, LCV and MTF varied depending on the protocols used for the linac CBCT. Contrast-to-noise ratio was an average of 51% higher for the CT than for the linac and simulator CBCT. No significant time trend was observed and tolerance limits were implemented.

Discussion: Reasonable differences in image quality between CT and CBCT were observed. Further research and development are necessary to increase image quality of commercially available CBCT devices in order for them to serve the needs for adaptive and/or online planning.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artifacts
  • Computer Simulation*
  • Cone-Beam Computed Tomography / instrumentation*
  • Cone-Beam Computed Tomography / methods
  • Contrast Media
  • Equipment Design
  • Equipment Safety
  • Humans
  • Phantoms, Imaging
  • Radiation Oncology / instrumentation
  • Radiation Oncology / methods
  • Radiographic Image Interpretation, Computer-Assisted / instrumentation*
  • Radiographic Image Interpretation, Computer-Assisted / methods
  • Radiography, Interventional
  • Radiotherapy Planning, Computer-Assisted / instrumentation
  • Radiotherapy, Computer-Assisted / instrumentation*
  • Radiotherapy, Conformal / instrumentation
  • Tomography, X-Ray Computed / instrumentation
  • Tomography, X-Ray Computed / methods
  • Total Quality Management

Substances

  • Contrast Media